1542 An Audit of Rates of Lynch Testing in Confirmed Colorectal Cancer Cases

Abstract Introduction 12% of cancers in the UK are colorectal origin1 with 1-3% secondary to genetic mismatch repair due Lynch syndrome2, for which 2017 NICE guidance recommended that patients cancer (CRC) be tested3. It increases risk developing other such as endometrial, ovarian and small bowel1, changes oncological treatment offered CRC patients4,5, prompts investigation their relatives condition. In this audit we assessed our rates trust wide testing. Method Patients a diagnosis from 2017-2019 were identified records held by services department. Histology results obtained an online portal. Results 345 included analysis, 79% tested Lynch, time taken biopsy ranging 2 276 days (average 45). 54% had within 30 days, 34% between 90 exceeded days. There was no significant difference testing each year. The proportion returned increased year, 30% (2017), 55% (2018) 71% (2019). median also improved, 39 28 16 respectively. Conclusions Rates efficiency screening lynch syndrome need improvement meet target suggested NICE. impact recent centralisation regions pathology department on service provision requires further investigation.